AQUASOMES DRUG DELIVERY PDF

Shaktigal This article reviews the principles of self assembly, the challenges of maintaining both the conformational integrity and biochemical activity of immobilized surface pairs, and the convergence of these principles into a single functional composition. Aquasomes discovery comprises a principle from microbiology, food chemistry, biophysics and many discoveries including solid phase synthesis, supramolecular chemistry, molecular shape change and vrug assembly. This property of maintaining the conformational integrity of bioactive molecules has led to the proposal that aquasomes have potential as a carrier system for delivery of peptide-based pharmaceuticals. Article Information Nanotechnology has emerged fields of biomedical research in the last few decades the presents context is an attempt to present the brief information ddug nanobiotechnological applications. Calcium phosphate is the core of interest, owing to its natural presence in the body. Aquasomes are one of the most recently developed delivery systems that are finding a niche as peptide and protein carriers.

Author:Fenrizil Arajin
Country:Algeria
Language:English (Spanish)
Genre:Politics
Published (Last):6 October 2012
Pages:183
PDF File Size:18.33 Mb
ePub File Size:1.44 Mb
ISBN:515-6-80728-808-9
Downloads:99708
Price:Free* [*Free Regsitration Required]
Uploader:Tajas



Shaktigal This article reviews the principles of self assembly, the challenges of maintaining both the conformational integrity and biochemical activity of immobilized surface pairs, and the convergence of these principles into a single functional composition. Aquasomes discovery comprises a principle from microbiology, food chemistry, biophysics and many discoveries including solid phase synthesis, supramolecular chemistry, molecular shape change and vrug assembly.

This property of maintaining the conformational integrity of bioactive molecules has led to the proposal that aquasomes have potential as a carrier system for delivery of peptide-based pharmaceuticals.

Article Information Nanotechnology has emerged fields of biomedical research in the last few decades the presents context is an attempt to present the brief information ddug nanobiotechnological applications.

Calcium phosphate is the core of interest, owing to its natural presence in the body. Aquasomes are one of the most recently developed delivery systems that are finding a niche as peptide and protein carriers. This article discusses the problems faced in the delivery of clinically important peptides and presents aquasomes as a reliable approach to troubleshoot them. The solid core provides the structural stability, while the carbohydrate coating protects against dehydration and stabilizes the biochemically active molecules.

Aquasome technology represents a patform system for conformational integrality and biochemical stability of bioactives. It is widely used for the preparation of implants for drug delivery. The solid core provides the structural stability, while the carbohydrate coating protects against dehydration and stabilizes drgu biochemically active molecules. Aquasomes: a promising carrier for peptides and protein delivery. The delivery system has been successfully utilized for the delivery of insulin, hemoglobin, and various antigens.

Their intended route of administration is parenteral and with advancement of research in this field, other routes might be contemplated. Department of Pharmacology, K. Three types of core materials are mainly used for producing aquasomes: Article Information Sr No: Aquasome deliver their content through specific targeting, molecular sheiling and slow sustained release process.

Aquasomes are spherical 60— nm particles used for drug and antigen delivery. Their large sized and active surfaces enable them to be loaded with water insoluble drugs through non covalent processes. Hydroxyapatite seems, therefore, a better core for the preparation of aquasomes. This property of maintaining the conformational integrity of bioactive molecules has led to the proposal that aquasomes have potential as a carrier system for delivery of peptide, protein, hormones, antigens and genes to specific sites.

These are nanoparticulate carrier systems with three-layered self-assembled structures. Nanobiopharmaceutics involves delivery of biopharmaceutical product through different biomaterials like multifunctional nanoparticles, quantum dots, aquasomes, superparamagnetic iron oxide crystals, and liposomes dendrimers.

They comprise a central solid nanocrystalline core coated with polyhydroxy oligomers onto which biochemically active molecules are adsorbed. Aquasomes are nanoparticulate carrier system but instead of being simple nanoparticles these arse three layered self assembled structures, comprised of a solid phase nanocrystalline core coated with oligomeric film to which biochemically active molecules are adsorbed with or without modification. Related Posts.

BUSZUJCY W ZBOU W PDF

AQUASOMES DRUG DELIVERY PDF

Nanotechnology has emerged fields of biomedical research in the last few decades the presents context is an attempt to present the brief information about nanobiotechnological applications. Aquasomes are nanoparticulate carrier system but instead of being simple nanoparticles these arse three layered self assembled structures, comprised of a solid phase nanocrystalline core coated with oligomeric film to which biochemically active molecules are adsorbed with or without modification. Aquasomes are spherical 60— nm particles used for drug and antigen delivery. Aquasomes discovery comprises a principle from microbiology, food chemistry, biophysics and many discoveries including solid phase synthesis, supramolecular chemistry, molecular shape change and self assembly.

ASHFAQ AHMED ZAVIA 2 PDF

Article Information

Kashura It is widely used for the preparation of implants for drug delivery. The solid core provides the structural stability, while the carbohydrate coating protects against dehydration and stabilizes the ddug active molecules. This article discusses the problems faced in the delivery of clinically important peptides and presents aquasomes as a reliable approach to troubleshoot them. This property of maintaining dleivery conformational integrity of bioactive molecules has led to the proposal that aquasomes have potential as a carrier system for delivery of peptide-based pharmaceuticals. Aquasomes: a promising carrier for peptides and protein delivery.

2SB737 DATASHEET PDF

AQUASOMES: A POTENTIAL APPROACH FOR NOVEL DRUG DELIVERY

Yozshugrel Their large sized and active surfaces enable them to be loaded with water insoluble drugs through non covalent processes. Calcium phosphate is the core of interest, owing to its natural presence in the body. Aquasomes are one of the most recently developed delivery systems that are finding a niche as peptide and protein carriers. Aquasome deliver their content through specific targeting, molecular sheiling and slow sustained release process. Three types of core materials are mainly used for producing aquasomes: The solid core provides the structural stability, while the carbohydrate coating protects against dehydration and stabilizes the biochemically active molecules. Aquasomes discovery comprises a principle from microbiology, food chemistry, biophysics and many discoveries including solid phase synthesis, supramolecular chemistry, molecular shape change and self assembly.

Related Articles